HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanesulfonyl chloride → N-Methyl-N-(5-methanesulphonamidobenzoxazol-2-ylmethyl)-4-methanesulphonamidophenethylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | N-methyl-N-(5-aminobenzoxazol-2-ylmethyl)-4-aminophenethylamine | HCID 19813431 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | N-Methyl-N-(5-methanesulphonamidobenzoxazol-2-ylmethyl)-4-methanesulphonamidophenethylamine | HCID 10389165 | — |
Reaction Steps
Methanesulphonyl chloride (0.38 g, 3.3 mmole) and N-methyl-N-(5-aminobenzoxazol-2-ylmethyl)-4-aminophenethylamine (see Preparation 1C--0.45 g, 1.5 mmole) in pyridine (20 ml) when reacted together under conditions similar to those of Example 2 gave the title compound, yield from ethanol 0.25 g, m.p. 174°-176°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04956382 |
| Source dataset | uspto-grants-1990_09 |
| ORD ID | ord-452584f191134906b775274e1b4a7b1f |
| Source note | uspto-grants-1990_09 |