Acetic Acid → HCID 14422911, compound

HRID 1032016Notes

Reaction equation

HRID 1032016 reaction equation
[C:1]([CH:3](C(OCC)=O)[C:4]1[C:13]([F:14])=[C:12]2[C:7]([C:8](=[O:23])[C:9]([C:18]([O:20]CC)=[O:19])=[CH:10][N:11]2[CH:15]2[CH2:17][CH2:16]2)=[CH:6][C:5]=1[F:24])#[N:2].C(O)(=O)C.S(=O)(=O)(O)O>O>[C:1]([CH2:3][C:4]1[C:13]([F:14])=[C:12]2[C:7]([C:8](=[O:23])[C:9]([C:18]([OH:20])=[O:19])=[CH:10][N:11]2[CH:15]2[CH2:16][CH2:17]2)=[CH:6][C:5]=1[F:24])#[N:2]

Participants

5

Reactant 3

HCID 176Acetic AcidHCID 1118Sulfuric AcidHCID 14422905HCID 14422905, compound

Product 1

HCID 14422911HCID 14422911, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

100 g of the compound from Example 1, 230 ml of acetic acid, 200 ml of water and 20 ml of sulphuric acid are boiled for 5 hours. After cooling to room temperature, water is added. The precipitated solid is isolated, washed with water and dried.

Workup

  1. customThe precipitated solid is isolated
  2. washwashed with water
  3. customdried

Sources & evidence

ORD record
ord-7f6fc7990b9a42c99b2221340984fb36
Source dataset
uspto-grants-1990_09
Patent number
US04956465

Reaction notes

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