HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methacrylamide → Ethyl [(2-methylacryloyl)amino](oxo)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methacrylamide | HCID 6595 | — |
| Reactant | Ethoxalyl chloride | HCID 20884 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | Ethyl [(2-methylacryloyl)amino](oxo)acetate | HCID 14298183 | 70.2% |
Reaction Steps
Into the same reaction vessel as used in Example 1, tetrahydrofuran (50 ml), methacrylamide (4.26 g; 50 mmol) and ethoxalyl chloride (6.83 g; 50 mmol) were charged, and refluxing was continued for 4 hours. Removal of the organic solvent by distillation under reduced pressure gave N-ethoxalylmethacrylamide (6.5 g). Yield, 70.6%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04956491 |
| Source dataset | uspto-grants-1990_09 |
| ORD ID | ord-38cc584a885647a3bda0cb1186226acd |
| Source note | uspto-grants-1990_09 |