1,3-Cyclohexanedione → HCID 15577767, compound

HRID 1032244Notes

Reaction equation

HRID 1032244 reaction equation
[I:1][C:2]1[CH:8]=[CH:7][CH:6]=[CH:5][C:3]=1[NH2:4].[C:9]1(=O)[CH2:14][CH2:13][CH2:12][C:11](=[O:15])[CH2:10]1>>[I:1][C:2]1[CH:8]=[CH:7][CH:6]=[CH:5][C:3]=1[NH:4][C:9]1[CH2:14][CH2:13][CH2:12][C:11](=[O:15])[CH:10]=1

Participants

3

Reactant 2

HCID 104341,3-CyclohexanedioneHCID 119952-Iodoaniline

Product 1

HCID 15577767HCID 15577767, compound

Procedure

A stirred mixture of 2-iodoaniline (22.2 g) and cyclohexane-1,3-dione (11.2 g) was heated under nitrogen at 120° for 1 h, cooled and the resulting solid pulverised under ether (300 ml). The mixture was filtered and the solid (30 g) recrystallised from acetone:hexane (1:1, 400 ml), giving the title compound as prisms m.p. 151°-3° (decomp.).

Workup

  1. temperaturewas heated under nitrogen at 120° for 1 h
  2. temperaturecooled
  3. filtrationThe mixture was filtered
  4. customthe solid (30 g) recrystallised from acetone:hexane (1:1, 400 ml)

Sources & evidence

ORD record
ord-5303e30588484edc903b1f28ab7f5498
Source dataset
uspto-grants-1990_09
Patent number
US04957609

Reaction notes

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