HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbon tetrabromide → 3-(2,2-Dibromoethenyl)-5-trimethylsilylfuran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbon tetrabromide | HCID 11205 | — |
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | 5-(Trimethylsilyl)furan-3-carbaldehyde | HCID 15663251 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-(2,2-Dibromoethenyl)-5-trimethylsilylfuran | HCID 19991587 | — |
Reaction Steps
5-Trimethylsilyl-3-furaldehyde is treated with carbon tetrabromide and triphenylphosphine in dichloromethane at 0° to give 3-(2,2-dibromoethenyl)-5-trimethylsilylfuran. Treating with n-butyl lithium and 5-phenylpentyl iodide and hexamethylphosphoramide gives 3-(7-phenyl-1-heptynyl)-5-trimethylsilylfuran.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04957917 |
| Source dataset | uspto-grants-1990_09 |
| ORD ID | ord-37cabc7bc2ca4ec581d6625176683b9a |
| Source note | uspto-grants-1990_09 |