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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1032354Generated: October 27, 2026

Acetyl chloride → 1-(Benzyloxycarbonyldiethylphosphono)methyl-3-azido-4-chloro-2-azetidinone

https://huagongshe.com/reaction/1032354

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetyl chlorideHCID 6367—
Reactant1-(Benzyloxycarbonyldiethylphosphono)methyl-3-azido-4-methylsulfonyl-2-azetidinoneHCID 86737251—
Product1-(Benzyloxycarbonyldiethylphosphono)methyl-3-azido-4-chloro-2-azetidinoneHCID 86737253—

Reaction Steps

1-(Benzyloxycarbonyldiethylphosphono)methyl-3-azido-4-methylsulfonyl-2-azetidinone (0.446 g.) is dissolved in acetyl chloride (5 ml.). The mixture is allowed to stand for 10 minutes and the acetyl chloride is removed under reduced pressure to afford 1-(benzyloxycarbonyldiethylphosphono)methyl-3-azido-4-chloro-2-azetidinone

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04957912
Source datasetuspto-grants-1990_09
ORD IDord-dae31e3e663746e7a030823b5b5aff37
Source noteuspto-grants-1990_09