Methyl Acrylate → N-[2-(chroman-3-yl)ethyl]-N,N-bis(2-methoxycarbonylethyl)-amine

Participants

Role	Name	HCID	Charge
Reactant	Methyl Acrylate	HCID 7294	—
Reactant	2-(3,4-dihydro-2H-1-benzopyran-3-yl)ethan-1-amine	HCID 14838408	—
Solvent	Methanol	HCID 887	—
Product	N-[2-(chroman-3-yl)ethyl]-N,N-bis(2-methoxycarbonylethyl)-amine	HCID 14838409	100%

Reaction Steps

6.63 g (77 mmol) of acrylic acid methyl ester are added at room temperature to a solution of 6.2 g (35 mmol) of 3-(2-aminoethyl)chroman in 50 ml of methanol and the whole is stirred for 16 hours at room temperature. The reaction mixture is then concentrated by evaporation in vacuo and yields 12.23 g (100%) of N-[2-(chroman-3-yl)ethyl]-N,N-bis(2-methoxycarbonylethyl)-amine in the form of a reddish oil.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US04957928
Source dataset	uspto-grants-1990_09
ORD ID	ord-355de56b303343358fb603a90e70eafc
Source note	uspto-grants-1990_09