Water → HCID 14851299, compound

Participants

Reaction Steps

Manganese IV dioxide (72.2 g, 0.83 mol) was suspended in toluene and refluxed for four hours with azeotropic removal of water. The unsaturated alcohol (28 g, 0.083 mol, Step B) was added and heating to reflux continued for 24 hours. The suspension was then cooled to room temperature and filtered through a bed of silica. The filtrate was concentrated in-vacuo to give 27.0 g of pure product (98%), mp 105°-107° C.

Provenance & Evidence