HCID 22165705, compound → HCID 15096545, compound

Participants

Reaction Steps

10% Palladium on charcoal (200 mg) was added under argon to a solution of 1-(4-chlorophenyl)-3-(1,2,4-triazol-1-yl)-2-(1,2,4-triazol-1-ylmethyl)propene (750 mg) in absolute ethanol (50 ml). After uptake of the theoretical amount of hydrogen, the reaction mixture was filtered through Kieselguhr ( Celite-- trademark) and evaporated to dryness under reduced pressure. The residual oil was purified by chromatography on silica, using chloroform as eluent, and after evaporation of the solvent, the residue was treated with ethereal hydrogen chloride to give 2-(4-chlorobenzyl)1,3-bis(1,2,4-triazol-1-yl)propane: m.p. 107 -108 °.

Provenance & Evidence