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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 103248Generated: October 26, 2026

8-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,4-dioxaspiro(4.5)dec-7-ene → N-(1-(4-(3-(methylamino)pyridin-4-yl)cyclohexyl)azetidin-3-yl)-2-((6-(trifluoromethyl)quinazolin-4-yl)amino)acetamide

https://huagongshe.com/reaction/103248

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,4-dioxaspiro(4.5)dec-7-eneHCID 3697076—
Reactant4-(3-(Methylamino)pyridin-4-yl)cyclohexanoneHCID 68003406—
ReactantN-(azetidin-3-yl)-2((6-(trifluoromethyl)quinazolin-4-yl)amino)acetamideHCID 68003594—
Reactant4-bromo-N-methylpyridin-3-amineHCID 68003905—
ProductN-(1-(4-(3-(methylamino)pyridin-4-yl)cyclohexyl)azetidin-3-yl)-2-((6-(trifluoromethyl)quinazolin-4-yl)amino)acetamideHCID 68004048—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-6b4c1fd0d6414471a11b6c4b1c20d1a4
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)