HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 4-(Benzyloxy)-3-nitrobenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Benzyl Chloride | HCID 7503 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Hydroxy-3-nitrobenzaldehyde | HCID 18169 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-(Benzyloxy)-3-nitrobenzaldehyde | HCID 7023554 | 83.6% |
Reaction Steps
At 100° C., 167.0 g of 4-hydroxy-3-nitrobenzaldehyde, 311.0 g of potassium carbonate, and 211.0 g of benzyl chloride are agitated in 2 l of dimethylformamide for 16 hours. The resultant reaction mixture is poured into 10 l of water, the thus-separated solid product is filtered off and recrystallized from ethanol, yielding 215.0 g of 4-benzyloxy-3-nitrobenzaldehyde, mp 100°-102° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04958026 |
| Source dataset | uspto-grants-1990_09 |
| ORD ID | ord-8e320f556b79439184d30adaf4029a84 |
| Source note | uspto-grants-1990_09 |