HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 2-(Benzyloxy)-4-methyl-1-nitrobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Benzyl Chloride | HCID 7503 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 6-Nitro-m-cresol | HCID 12788 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-(Benzyloxy)-4-methyl-1-nitrobenzene | HCID 13629304 | — |
Reaction Steps
61.2 g of 3-hydroxy-4-nitrotoluene, 66.3 g of potassium carbonate, and 54.7 ml of benzyl chloride are heated in 800 ml of dimethylformamide to 100° C. for 1.5 hours; after cooling, the mixture is poured into water, and the thus-precipitated material is recrystallized from ethanol, yielding 82.0 g of 3-benzyloxy-4-nitrotoluene, mp 49°-51° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04958026 |
| Source dataset | uspto-grants-1990_09 |
| ORD ID | ord-e8d9e7cfa91741b4b83133dbbdc0a416 |
| Source note | uspto-grants-1990_09 |