反应详情

16.0 g of 3-benzyloxy-4-nitrotoluene and 23.0 g of tert-butoxybis(dimethylamino)methane are heated for 8 hours to 100° C. After allowing the mixture to stand for 8 hours at room temperature, the pure reaction product is crystallized. This product is filtered off and washed with a mixture of ethyl acetate and cyclohexane 1:4, thus obtaining 18.7 g of 1-(3-benzyloxy-4-nitrophenyl)-2-dimethylaminoethene, mp 111°-114° C.

1. customthe pure reaction product is crystallized
2. filtrationThis product is filtered off
3. washwashed with a mixture of ethyl acetate and cyclohexane 1:4