HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-Benzyloxy-4-nitrophenyl)-2-dimethylaminoethene → (3-Benzyloxy-4-nitrophenyl)acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-Benzyloxy-4-nitrophenyl)-2-dimethylaminoethene | HCID 54049086 | — |
| Solvent | Water | HCID 962 | — |
| Product | (3-Benzyloxy-4-nitrophenyl)acetonitrile | HCID 13629306 | 45.8% |
Reaction Steps
18.7 g of N-[2-(3-benzyloxy-4-nitrophenyl)ethenyl]-N,N-dimethylamine and 21.3 g of hydroxylamineorthosulfonic acid in 420 ml of water are stirred for 3 days at room temperature. The thus-separated solid product is chromatographed on silica gel with cyclohexane/acetic acid (1:1), thus obtaining 7.7 g of (3-benzyloxy-4-nitrophenyl)acetonitrile, mp 73°-85° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04958026 |
| Source dataset | uspto-grants-1990_09 |
| ORD ID | ord-22bb6ba83c244b488df30ab3579dde84 |
| Source note | uspto-grants-1990_09 |