HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(3-Benzyloxy-4-nitrophenyl)ethylamine, hydrochloride → 2-(4-Amino-3-benzyloxyphenyl)ethylamine, Hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(3-Benzyloxy-4-nitrophenyl)ethylamine, hydrochloride | HCID 131716565 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-(4-Amino-3-benzyloxyphenyl)ethylamine, Hydrochloride | HCID 22165998 | — |
Reaction Steps
In the presence of Raney nickel, 3.2 g of 2-(3-benzyloxy-4-nitrophenyl)ethylamine, hydrochloride, is hydrogenated in 50 ml of methanol, thus producing, after recrystallizing the product from ethanol, 1.36 g of 2-(4-amino-3-benzyloxyphenyl)ethylamine, hydrochloride, mp 181°-184° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04958026 |
| Source dataset | uspto-grants-1990_09 |
| ORD ID | ord-78362eb093824b34a4414f82ea1384bc |
| Source note | uspto-grants-1990_09 |