HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-tert-Butoxy-N,N,N',N'-tetrapropylmethanediamine → N,N-dipropyl-N-[2-(7-nitro-1H-indazol-4-yl)ethenyl]amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-tert-Butoxy-N,N,N',N'-tetrapropylmethanediamine | HCID 13771313 | — |
| Reactant | 4-Methyl-7-nitro-1H-indazole | HCID 22166018 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | N,N-dipropyl-N-[2-(7-nitro-1H-indazol-4-yl)ethenyl]amine | HCID 54102292 | 90.7% |
Reaction Steps
2.1 g of 4-methyl-7-nitro-1H-indazole and 5.0 g of tert-butoxybis(dipropylamino)methane are heated to 80° C. in 10 ml of tetrahydrofuran for 2.5 hours. The mixture is concentrated, distilled with tetrahydrofuran, and recrystallized from dichloromethane/hexane, yielding 3.1 g of N,N-dipropyl-N-[2-(7-nitro-1H-indazol-4-yl)ethenyl]amine, mp 166°-167° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04958026 |
| Source dataset | uspto-grants-1990_09 |
| ORD ID | ord-76073e69a49c4844a03b0e57a7e14f84 |
| Source note | uspto-grants-1990_09 |