HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-dimethyl-N-[2-(7-nitro-1H-indazol-4-yl)ethenyl]amine → 2-(7-nitro-1H-indazol-4-yl)acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-dimethyl-N-[2-(7-nitro-1H-indazol-4-yl)ethenyl]amine | HCID 54098844 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-(7-nitro-1H-indazol-4-yl)acetonitrile | HCID 13629308 | 78.9% |
Reaction Steps
At room temperature, 23.3 g of N,N-dimethyl-N-[2-(7-nitro-1H-indazol-4-yl)ethenyl]amine and 35.0 g of hydroxylamine-orthosulfonic acid are agitated in 400 ml of water for 24 hours. The precipitate is suctioned off, washed with water, and recrystallized from ethyl acetate, thus obtaining 16.0 g of 2-(7-nitro-1H-indazol-4-yl)acetonitrile, mp 198°-200° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04958026 |
| Source dataset | uspto-grants-1990_09 |
| ORD ID | ord-a29ec0adc9fb4b87a8123b7be4c25b04 |
| Source note | uspto-grants-1990_09 |