Benzylamine → HCID 13629341, compound

HRID 1032545Notes

Reaction equation

HRID 1032545 reaction equation
[OH:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:11][C:12]([OH:14])=O)=[C:6]2[C:10]=1[NH:9][N:8]=[CH:7]2.[CH2:15]([NH2:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[CH2:15]([NH:22][C:12](=[O:14])[CH2:11][C:5]1[CH:4]=[CH:3][C:2]([OH:1])=[C:10]2[C:6]=1[CH:7]=[N:8][NH:9]2)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 7504BenzylamineHCID 13629338HCID 13629338, compound

Product 1

HCID 13629341HCID 13629341, compound

Procedure

2.3 g of 2-(7-hydroxy-1H-indazol-4-yl)acetic acid is reacted analogously to Example 19(c) with benzylamine in place of dipropylamine. The product is recrystallized from methanol/diisopropyl ether, thus obtaining 2.6 g of 2-(7-hydroxy-1H-indazol-4-yl)acetic acid benzylamide, mp 188°-190° C.

Workup

  1. customThe product is recrystallized from methanol/diisopropyl ether

Sources & evidence

ORD record
ord-544b3259e44f46b58e5eda69c3b87ef2
Source dataset
uspto-grants-1990_09
Patent number
US04958026

Reaction notes

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