1,1'-Thiocarbonyldiimidazole → HCID 13771336, compound

Participants

Reaction Steps

500 mg of N-[2-(2,3-diamino-4-methoxyphenyl)ethyl]-N,N-dimethylamine is heated for 3 hours under reflux with 50 ml of tetrahydrofuran and 430 mg of N,N'-thiocarbonyldiimidazole. After concentration, the residue is combined with water. The precipitate is recrystallized from ethanol, thus obtaining 470 mg of 7-methoxy-4-[2-(N,N-dimethylamino)ethyl]-2,3-dihydro-2-benzimidazolethione, mp 213°-216° C.

Provenance & Evidence