N,O-Dimethylhydroxylamine → HCID 14499865, compound

Participants

Reaction Steps

1.8 g of 4-(2,3-dihydro-2,2-dimethyl-4-benzofuranylmethyloxy)phenyl isocyanate was dissolved into 20 ml of toluene, and 2.0 g of N,O-dimethylhydroxylamine dissolved in 5 ml of toluene was slowly added dropwise thereto at room temperature. After the mixture was stirred at room temperature for 2 hours, toluene was distilled off and the residue was subjected to silica gel column chromatography using ethyl acetate/n-hexane (1/4) as a developer to obtain 1.8 g of Compound No. 6 shown in Table 1.

Provenance & Evidence