Formic Acid → HCID 131716583, compound

HRID 1032632Notes

Reaction equation

HRID 1032632 reaction equation
[CH3:1][C:2]1([CH3:13])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]([CH2:11][OH:12])[CH2:3]1.[CH:14](O)=[O:15]>>[CH3:1][C:2]1([CH3:13])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]([CH2:11][O:12][CH:14]=[O:15])[CH2:3]1

Participants

3

Reactant 2

HCID 284Formic Acid2×HCID 15105986HCID 15105986, compound

Product 1

HCID 131716583HCID 131716583, compoundYield 82%

Procedure

17.6 g (0.1 mol) of 1,1-dimethyl-3-hydroxymethylindane (IX) and 46.0 g (1.0 mol) of formic acid were reacted at room temperature for 16 hours while stirring. After the reaction, surplus formic acid was removed under reduced pressure. The residue was extracted with ether, washed with aqueous sodium bicarbonate, and dried over anhydrous magnesium sulfate. The solvent was removed from the organic layer and the residue was distilled under reduced pressure to produce 16.8 g (0.82 mol) of (1,1-dimethylindane-3-yl)methylformate at a yield of 82%. The product was a colorless, transparent liquid having a woody, green odor similar to green tea with a scent of rush.

Workup

  1. customwas removed under reduced pressure
  2. extractionThe residue was extracted with ether
  3. washwashed with aqueous sodium bicarbonate
  4. dry with materialdried over anhydrous magnesium sulfate
  5. customThe solvent was removed from the organic layer
  6. distillationthe residue was distilled under reduced pressure

Sources & evidence

ORD record
ord-a8f092d6ccb047bcab48f8a6e3792371
Source dataset
uspto-grants-1990_09
Patent number
US04959349

Reaction notes

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