HCID 15105986, compound → HCID 22164638, compound

Participants

Reaction Steps

11.3 g (64 mmol) of 1,1-dimethyl-3-hydroxymethylindane (IX), 3 g of 5% luthenium-carbon (manufactured by Engerhard Industries Corp.), and 300 ml of ethanol was placed in a 100 ml autoclave. After internal air was displaced by hydrogen, the mixture was heated at an initial hydrogen pressure of 100 kg/cm2. The reaction temperature reached 140° C. 1 hour after the heating was started. The absorption of hydrogen terminated when the reaction was continued at this temperature for 7 hours. After cooling, the pressure was released and the catalyst was separated out by filtration. The filtrate was distilled under reduced pressure to produce 9.7 g (53 mmol) of the title compound (Ic) at a yield of 83%. Capillary gas chromatography analysis revealed that the compound is comprised of two major components each having a peak of which the area ratio was 59:41.

Provenance & Evidence