Trichloroacetic Acid → HCID 131716586, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 2-O-octadecyl-L-ascorbic acid (0.8 g, 2 mmole) and phenylisocyanate (0.24 g, 2 mmole) in chloroform (20 ml) was added trichloracetic acid (0.1 ml). The mixture was heated at 60° C. for one hour, which was washed with water, dried and concentrated to give a product. The product was recrystallized from isopropyl ether - ethyl acetate to give 6-O-phenylcarbamoyl-2-O-octadecyl-L-ascorbic acid (0.75 g), m.p. 149°-150° C. C31H49NO7 (Found: C,68.14; H,9.08; N,2.74%. Anal. Calcd: C,67.98; H,9.02; N,2.56).

Provenance & Evidence