HRID1032671

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID31297

Methanesulfonyl chloride

CH3ClO2S

结构：CN(CCOc1ccc(N)cc1)CCc1ccc(NS(C)(=O)=O)cc1.CN(CCOc1ccc(N)cc1)CCc1ccc(NS(C)(=O)=O)cc1.Cl.Cl.Cl.Cl.O

HCID67895548

未命名化合物

PRODUCTS

生成物

结构：CN(CCOc1ccc(NS(C)(=O)=O)cc1)CCc1ccc(NS(C)(=O)=O)cc1

HCID71329

Dofetilide

C19H27N3O5S2

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID1049

Pyridine

C5H5N

PROCEDURE

实验过程

The title compound was prepared by mesylation of 1-(4-aminophenoxy)-2-[N-methyl-N-(4-methanesulphonamidophenethyl)amino]ethane dihydrochloride hemihydrate (95 mg) with mesyl chloride ir pyridine according to the procedure of Example 19(C), yield 30 mg, m.p. 147°-149°, confirmed spectroscopically to be identical to the product of Example 7(C).