Methanesulfonyl chloride → HCID 19915737, compound

HRID 1032676Notes

Reaction equation

[NH2:1][C:2]1[CH:21]=[CH:20][C:5]([CH2:6][CH2:7][N:8]([CH2:18][CH3:19])[CH2:9][CH2:10][C:11]2[CH:16]=[CH:15][C:14]([NH2:17])=[CH:13][CH:12]=2)=[CH:4][CH:3]=1.[CH3:22][S:23](Cl)(=[O:25])=[O:24]>>[CH3:22][S:23]([NH:17][C:14]1[CH:15]=[CH:16][C:11]([CH2:10][CH2:9][N:8]([CH2:18][CH3:19])[CH2:7][CH2:6][C:5]2[CH:4]=[CH:3][C:2]([NH:1][S:23]([CH3:22])(=[O:25])=[O:24])=[CH:21][CH:20]=2)=[CH:12][CH:13]=1)(=[O:25])=[O:24]

Participants

Reactant 2

HCID 31297Methanesulfonyl chloride

HCID 19915723HCID 19915723, compound

Product 1

HCID 19915737HCID 19915737, compound

Procedure

N,N-Bis-(4-aminophenethyl)ethylamine (0.3 g) was acylated with methanesulphonyl chloride in a similar fashion to Example 19(C) to produce the title compound as a foam, yield 0.12 g, m.p. <60°.

Sources & evidence

ORD record: ord-ec4b6f042b4f4c97854ab35dfe2c4f98
Source dataset: uspto-grants-1990_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04959366

Reaction notes

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