1,1-Dimethoxyethyl(dimethyl)amine → HCID 53773844, compound

Participants

Reaction Steps

A mixture of 32.6 g ethyl 7-acetyl-1,4-dihydro1-ethyl-4-oxo-3-quinolinecarboxylate, 24 ml dimethylacetamide dimethylacetal and 100 ml DMF was heated on a steam bath for 4 hrs. The reaction mixture was concentrated in vacuo and the solid residue triturated with ethyl acetate. The solid product was recrystallized from acetonitrile to give 20.9 g ethyl 7-[3-(dimethylamino)-1-oxo2-butenyl]-1-ethyl-1,4-dihydro-4-oxo-3-quinolinecarboxylate, yellowish-orange powder, m.p. 178-179.5° C.

Provenance & Evidence