HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromopyridine → 3-(Trimethylstannyl)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromopyridine | HCID 12286 | — |
| Reactant | Trimethyltin chloride | HCID 14016 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Product | 3-(Trimethylstannyl)pyridine | HCID 10868445 | — |
Reaction Steps
The 3-trimethylstannylpyridine reagent was prepared from 3-bromopyridine by reacting the latter with n-butyllithium under nitrogen at -78° C., followed by addition of one equivalent of trimethylstannyl chloride. Aqueous work-up and concentration in vacuo gave 3-trimethylstannylpyridine in 79% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04959363 |
| Source dataset | uspto-grants-1990_09 |
| ORD ID | ord-bab09fc23c664c84a9f41948abd23dda |
| Source note | uspto-grants-1990_09 |