1-(4-Fluorophenyl)-4-oxo-7-(4-pyridyl)quinoline-3-carboxamide → 7-Chloro-1-(4-fluorophenyl)-4-oxo-quinoline-3-carboxamide

Participants

Reaction Steps

7-Chloro-1,4-dihydro-4-oxo-1-phenyl-3-quinolinecarboxamide [IV; R=H, R1 =C6H5, R2 =H, R6 =H, X=Cl]was prepared from 3.60 g 7-chloro-1,4-dihydro-4-oxo-1-phenyl3-quinolinecarboxylic acid by the procedure of Example 1, part (h), and was obtained (3.00 g) in the form of a colorless solid, m.p. 297-299° C. when recrystallized from DMF.

Provenance & Evidence