HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-chlorophenyl)-2-iodo-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine → HCID 14851872, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-chlorophenyl)-2-iodo-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine | HCID 14851924 | — |
| Reactant | HCID 14851943 | HCID 14851943 | — |
| Product | HCID 14851872 | HCID 14851872 | — |
Reaction Steps
Coupling of 4-(2-chlorophenyl)-2-iodo-9-methyl-6H-thieno[3,2-f][1,2,4] triazolo[4,3-a][1,4]diazepine with 2-(3-butyn-1-yl)-1H-benz[de]isoquinoline-1,3(2H)-dione as described in Example 37 yielded after chromatography and crystallization from ethyl acetate light yellow crystals of the title compound with m.p. 175°-179° C. A higher melting crystalline modification with m.p. 227°-229° C. was also observed.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04959361 |
| Source dataset | uspto-grants-1990_09 |
| ORD ID | ord-c35f80c58937418796aeca4404cbfec1 |
| Source note | uspto-grants-1990_09 |