HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → HCID 10357235, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | Syringaldehyde | HCID 8655 | — |
| Reactant | tert-Butyldimethylsilyl chloride | HCID 28928 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 10357235 | HCID 10357235 | — |
Reaction Steps
Using the conditions described in Example 14c 2.05 g of 3,5-dimethoxy-4-hydroxybenzaldehyde were reacted with 2.05 g of tertbutyldimethylchlorosilane in the presence of 0.91 g of imidazole and 15 ml of absolute dimethylformamide. The crude product was purified by chromatography on silica gel [Kieselgel 60 (0.063-0.200 mm)] with petroleum ether/ether (1:1) whereupon 2.91 g of the title compound were obtained in the form of crystals melting at 68° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04959391 |
| Source dataset | uspto-grants-1990_09 |
| ORD ID | ord-0a72b4a4e94d4609a7a5b40934610483 |
| Source note | uspto-grants-1990_09 |