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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1032810Generated: October 31, 2026

Hydrochloric Acid → (2R,3R,4S,5R)-2-amino-3,4,5,6-tetrahydroxyhexanal

https://huagongshe.com/reaction/1032810

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantSodium BicarbonateHCID 516892—
Reactant(3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol hydrochlorideHCID 2723635—
ReactantSodium cyanoborohydrideHCID 5003444—
Product(2R,3R,4S,5R)-2-amino-3,4,5,6-tetrahydroxyhexanalHCID 3034366—

Reaction Steps

Reactions of carboxymethyl cellulose sodium salt (0.5-1.0% w/v) were carried out with glucosamine-hydrochloride (1.5-3.0% w/v) in the presence of equimolar amounts of base, such as a sodium bicarbonate solution (0.55-1.1% w/v) to neutralize the hydrochloride, sodium cyanoborohydride as reducing reagent (0.27-0.50% w/v), at room temperature, producing 2-amino-2-deoxy-glucose derivatives of carboxymethyl cellulose with nitrogen incorporation values of 2.60-3.07%, as shown in Table 2, page 17.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04959461
Source datasetuspto-grants-1990_09
ORD IDord-a813bd79ab244967a6d468f87f5d51df
Source noteuspto-grants-1990_09