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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1032873Generated: October 30, 2026

Hydroxyphenylacetic acid → Ethyl 4-hydroxyphenylacetate

https://huagongshe.com/reaction/1032873

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydroxyphenylacetic acidHCID 127—
ReactantEthanolHCID 702—
ReactantSulfuric AcidHCID 1118—
ProductEthyl 4-hydroxyphenylacetateHCID 28310—

Reaction Steps

4-Hydroxyphenylacetic acid (50.0 g) is dissolved in ethanol (400 ml) and thereto is added conc. sulfuric acid (0.5 ml). The mixture is refluxed with stirring, and ethanol is distilled off to give ethyl 4-hydroxyphenylacetate (60 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05308540
Source datasetuspto-grants-1994_05
ORD IDord-32f879451f964ba884cac894f3d81ef7
Source noteuspto-grants-1994_05