HCID 19027052, compound → HCID 19027059, compound

Participants

Reaction Steps

A suspension of 1,2,3,4-tetrahydro-8-nitro-5-naphthalenesulfonamide (3.1 g, 12 mmol) in 150 ml of ethanol was hydrogenated at room temperature and atmospheric pressure over Raney-Ni. After the theoretical absorption, the reaction mixture was filtered and concentrated to dryness to give 2.6 g (95%) of the title compound. M.p. 216°-219° C. (ethanol); 1H-NMR (DMSO-d6): 1.50-1.93 (m, 4H, 2CH2), 2.17-2.57 (m, 2H, CH2), 2.83-3.17 (m, 2H, CH2), 5.29 (broad s, 2H, NH2), 6.38 (d,J =9Hz, 1H, ArH), 6.75 (broad s, 1H, SO2NH2), 7.35 (d,J =9Hz, 1H, ArH).

Provenance & Evidence