1,4-Dioxane → N-[4-(benzyloxy)phenyl]-6-(1-methyl-1H-imidazol-5-yl)quinazolin-4-amine

HRID 103298Notes

Reaction equation

HRID 103298 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12]([NH:15][c:16]2[n:17][cH:18][n:19][c:20]3[cH:21][cH:22][c:23]([Br:26])[cH:24][c:25]23)[cH:13][cH:14]1.[CH3:27][n:28]1[cH:29][n:30][cH:31][c:32]1[Sn:33]([CH2:34][CH2:35][CH2:36][CH3:37])([CH2:38][CH2:39][CH2:40][CH3:41])[CH2:42][CH2:43][CH2:44][CH3:45].[O:46]1[CH2:47][CH2:48][O:49][CH2:50][CH2:51]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12]([NH:15][c:16]2[n:17][cH:18][n:19][c:20]3[cH:21][cH:22][c:23](-[c:32]4[n:28]([CH3:27])[cH:29][n:30][cH:31]4)[cH:24][c:25]23)[cH:13][cH:14]1

Participants

4

Reactant 3

HCID 312751,4-DioxaneHCID 1569266(6-Bromoquinazolin-4-yl)[4-(phenylmethoxy)phenyl]amineHCID 109156511-Methyl-5-(tri-n-butylstannyl)imidazole

Product 1

HCID 22609863N-[4-(benzyloxy)phenyl]-6-(1-methyl-1H-imidazol-5-yl)quinazolin-4-amine

Sources & evidence

ORD record
ord-3ed9fe37bc30442f8acf706d2b294726
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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