反应详情

Into 30 ml of dioxane were dissolved 1,00 g of 5-(4-amino-phenyl)thiazolidine-2,4-dione and 0.74 g of phthalic anhydride, and the solution was refluxed for 2 hours. Thereafter, 30 ml of acetic acid and 0.5 g of sodium acetate were added and the mixture was refluxed for 2 hours. The reaction liquor was poured into 400 ml of water, and the crystals deposited were collected by filtration. These were recrystalized from ethanol to obtain 1.50 g of title compound.

1. temperaturethe solution was refluxed for 2 hours
2. temperaturethe mixture was refluxed for 2 hours
3. filtrationthe crystals deposited were collected by filtration
4. customThese were recrystalized from ethanol