HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Acetate → Methyl 4-[(2-butyl-5-formyl-1H-imidazol-1-YL)methyl]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Acetate | HCID 517044 | — |
| Reactant | HCID 14952880 | HCID 14952880 | — |
| Reactant | Ethyl acetate hexane | HCID 21226206 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 4-[(2-butyl-5-formyl-1H-imidazol-1-YL)methyl]benzoate | HCID 10334966 | — |
Reaction Steps
A solution of 1.00 g (0.003 mole) of 2-butyl-1-(4-carbomethoxybenzyl)-4-chloro-5-formylimidazole in 75 mL of methanol is reduced at low pressure with hydrogen and 0.30 g of 5% Pd/carbon in the presence of 0.30 g of potassium acetate to give product; mp 62°-64° C.; tlc (1:1 hexane-ethyl acetate) 1 spot, Rf 0.2; MS (CI) 301 (M+ +1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05308853 |
| Source dataset | uspto-grants-1994_05 |
| ORD ID | ord-73b2566e6abb4fda917a45a40c81252b |
| Source note | uspto-grants-1994_05 |