HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Carbonate → (4R)-4-phenyl-1,3-oxazolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Carbonate | HCID 7766 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | (R)-beta-aminophenethyl alcohol | HCID 2724025 | — |
| Product | (4R)-4-phenyl-1,3-oxazolidin-2-one | HCID 730425 | — |
Reaction Steps
7.54 g (55 mmol) of (2R)-(-)-2-amino-2-phenylethanol are dissolved in 8 ml (61 mmol) of diethyl carbonate, 770 mg (5.5 mmol) of K2CO3 are added, and ethanol is removed by distillation via a column. The crude product is recrystallized from ether/petroleum ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05310499 |
| Source dataset | uspto-grants-1994_05 |
| ORD ID | ord-00e65762665e4fb6b800b9a35748a245 |
| Source note | uspto-grants-1994_05 |