Methylhydrazine → HCID 19025420, compound

HRID 1033175Notes

Reaction equation

HRID 1033175 reaction equation
[CH3:1][C:2]([C:4]1[CH:5]=[C:6]([N:10]=[C:11]=[S:12])[CH:7]=[CH:8][CH:9]=1)=[O:3].[CH3:13][NH:14][NH2:15]>C(O)C>[CH3:13][N:14]([C:11]([NH:10][C:6]1[CH:7]=[CH:8][CH:9]=[C:4]([C:2]([CH3:1])=[O:3])[CH:5]=1)=[S:12])[NH2:15]

Participants

4

Reactant 2

HCID 6061MethylhydrazineHCID 5205153-Acetylphenylisothiocyanate

Product 1

HCID 19025420HCID 19025420, compoundYield 78.9%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Following procedures similar to those employed in Step A of Example 2, the reaction of 20.0 g (0.113 mole) of 3-methylcarbonylphenyl isothiocyanate and 5.21 g (0.113 mole) of methylhydrazine in 150 ml of ethanol yielded 19.9 g of 2-methyl-4-(3-methylcarbonylphenyl)-3-thiosemicarbazide as a solid, mp 125°-127° C. The nmr spectrum was consistent with the proposed structure.

Sources & evidence

ORD record
ord-2945fa2c0f2b4028a08a696207a8f322
Source dataset
uspto-grants-1994_05
Patent number
US05310724

Reaction notes

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