Diisobutylaluminumhydride → HCID 19922837, compound

HRID 1033200Notes

Reaction equation

[C:1]1([C@@H:7]2[O:17][C@@H:10]3[CH2:11][CH2:12][CH2:13][C@@H:14]([C:15]#[N:16])[N:9]3[C@@H:8]2[CH3:18])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[H-].C([Al+]CC(C)C)C(C)C>>[NH2:16][CH:15]1[CH:14]2[CH2:13][CH2:12][CH2:11][CH2:10][N:9]2[CH:8]([CH3:18])[CH:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[O:17]1

Participants

Reactant 2

HCID 21225700Diisobutylaluminumhydride

HCID 67807772HCID 67807772, compound

Product 1

HCID 19922837HCID 19922837, compound

Procedure

This compound is prepared from (2S,3R,5S,8aR)-2-phenyl-3-methyl-5-cyanooxazolidino[3,2-a]piperidine by reduction with diisobutylaluminum hydride as in stage III of Example 1.

Sources & evidence

ORD record: ord-812d7105fb3e4b76986242d87b28d69c
Source dataset: uspto-grants-1994_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05310739

Reaction notes

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