Ozone → HCID 56999087, compound

Participants

Reaction Steps

A dichloromethane solution of the product of Example 16B (1 g) is cooled to -78° C. and a stream of ozone is passed through the solution until a blue color persists. Excess ozone is removed with nitrogen ebullition and dimethyl sulfide (1 mL) is added. The reaction is allowed to warm to room temperature and stirred overnight. The solvents are removed under reduced pressure, and the title compound is obtained following purification by silica gel chromatography.

Provenance & Evidence