反应详情

25 g of 2-(3-(2,5-dimethylphenoxy)propyl)-2-methylpropionyl chloride are added to 14 g of (cis) 3,3,5-trimethylcyclohexanol dissolved in 100 ml of toluene. The mixture is refluxed for three hours and then evaporated to dryness. The evaporation residue is chromatographed on a silica column with chloroform. The title product is obtained in the amorphous state and in thin layer chromatography gives a single spot under the above conditions; the characteristic bands of its IR spectrum run in KBr are as follows: 3000-2850 cm-1, group of fine bands; 1730 cm-1, strong band for the carbonyl.

1. temperatureThe mixture is refluxed for three hours
2. customevaporated to dryness
3. customThe evaporation residue is chromatographed on a silica column with chloroform