Sodium borohydride → HCID 57209282, compound

Participants

Reaction Steps

185 mg (0.411 mmol) of the mixture of (2R*,4S *)-2-benzyl-1-((R)-N-acetyl-phenylalanyl)N-(4-quinolylmethyl)-N-trifluoroacetyl-4-piperidinamine diastereomers are reacted with 62 mg (1.64 mmol) of sodium borohydride in analogy to Example 2. The title compound ##STR58## is obtained as mixture of diastereomers (white foam). TLC: methylene chloride/methanol/conc. ammonia (700:50:1) Rf =0.42, FD-MS: M+ =520.

Provenance & Evidence