Triethylamine → HCID 57050179, compound

Participants

Reaction Steps

200 mg (0.468 mmol) of (2R*,4S*)-2-benzyl-N-(4-quinolylmethyl)-N-trifluoroacetyl-4-piperidinamine are reacted in analogy to Example 35a with 91 μl (0.655 mmol) of triethylamine and 80 μl (0.561 mmol) of 2,6-dichlorobenzoyl chloride to give the title compound (158 mg, 56%). TLC: methylene chloride/methanol/conc. ammonia (700:50:1) Rf =0.62, FD-MS: M+ =599, 601.

Provenance & Evidence