Sodium borohydride → HCID 57136956, compound

Participants

Reaction Steps

0.248 g (0.446 mmol) of (2R*,4S*)-2-benzyl-1-(3-cyanobenzoyl)-N-(4-quinolylmethyl)-N-trifluoroacetyl-4-piperidinamine is reacted with 0.068 g (1.78 mmol) of sodium borohydride in analogy to Example 2. The title compound ##STR74## is obtained (0.157 g, 62%) as white foam. TLC: methylene chloride/methanol/conc. ammonia (700:50:1) Rf =0.51, FD-MS: M+ =460.

Provenance & Evidence