HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-3-Amino-4,5-dihydro-1H-benzo[b]azepin-2(3H)-one → 3-Benzyloxycarbonylamino-3-methyl-N-[2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepin-3(S)-yl]-butanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-3-Amino-4,5-dihydro-1H-benzo[b]azepin-2(3H)-one | HCID 10241317 | — |
| Reactant | 3-(((Benzyloxy)carbonyl)amino)-3-methylbutanoic acid | HCID 14551007 | — |
| Product | 3-Benzyloxycarbonylamino-3-methyl-N-[2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepin-3(S)-yl]-butanamide | HCID 18651462 | — |
Reaction Steps
Prepared from 3(S)-amino-2,3,4,5-tetrahydro-1H-1-benzazepin-2-on (Example 1, Step B) and 3-benzyloxycarbonylamino-3-methylbutanoic acid (Example 1, Step E) by the procedure described in Example 1, Step F. FAB-MS: calculated for C23H27N3O4 409; found 410 (M+H,100%). [a]D =-160° (C=1,CHCl3).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05310737 |
| Source dataset | uspto-grants-1994_05 |
| ORD ID | ord-c7452847358b4d96865ded3a4b4a74ac |
| Source note | uspto-grants-1994_05 |