HCID 3328476, compound → 4-Methyl[1,1'-biphenyl]-2-amine

HRID 1033411Notes

Reaction equation

HRID 1033411 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([CH3:16])[CH:7]=[CH:8][C:9]=1[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)([O-])=O>CO.[Pd]>[NH2:1][C:4]1[CH:5]=[C:6]([CH3:16])[CH:7]=[CH:8][C:9]=1[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

4

Reactant 1

HCID 3328476HCID 3328476, compound

Product 1

HCID 125594574-Methyl[1,1'-biphenyl]-2-amineYield 96%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A solution of 2.4 g of 3-nitro-4-phenyltoluene in 25 mL of methanol was hydrogenated at room temperature and 40 psi over 0.30 g of 5% Pd/C catalyst. The solution was filtered and the filtrate concentrated to give 1.98 g of product. EI-MS: calculated for C13H13N: 183; found 183.

Workup

  1. customwas hydrogenated at room temperature
  2. filtrationThe solution was filtered
  3. concentrationthe filtrate concentrated

Sources & evidence

ORD record
ord-40b626294f5e46089d9f4e8333bad4cc
Source dataset
uspto-grants-1994_05
Patent number
US05310737

Reaction notes

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