Formaldehyde → HCID 54200907, compound

HRID 1033490Notes

Reaction equation

HRID 1033490 reaction equation
[C:1]1([C@@H:7]([NH:9][CH2:10][Si:11]([CH3:14])([CH3:13])[CH3:12])[CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:15]=[O:16]>C(O)CCCCCCC>[C:1]1([C@@H:7]([N:9]([CH2:10][Si:11]([CH3:13])([CH3:12])[CH3:14])[CH2:15][O:16][CH2:8][CH2:7][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH3:6])[CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 712FormaldehydeHCID 13526351HCID 13526351, compound

Product 1

HCID 54200907HCID 54200907, compound

Reagents, catalysts & solvents 1

HCID 9571-OctanolSolvent

Procedure

The title compound was prepared from (S)-(-)-N-1-phenylethyl-N-trimethylsilylmethylamine by reaction with n-octanol and aqueous formaldehyde following the procedure of Example 2 to give the crude acetal (90% pure) as a colourless oil (9.1 g, 91%)δC (CD2Cl2)--1.28 (SiMe3), 14.29, 23.08, 30.31, 29.74, 29.89, 26.82, 33.32, 63.13 (O Octyl), 19.37 (CMe), 40.11 (NCH2Si), 62.10 (CH), 84.69 (NCH2O), 126.82, 127.96, 128.31, 145.95 (Ph).

Sources & evidence

ORD record
ord-bce3fff1fb764b588b7593070b5e491e
Source dataset
uspto-grants-1994_05
Patent number
US05310911

Reaction notes

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