Hydrochloric Acid → HCID 178503132, compound

Participants

Reaction Steps

3.0 g (0.02 mol) of 4-(methylthio)benzonitrile, 1.44 g (0.022 mol) of sodium azide and 0.12 g (0.0022 mol) of ammonium chloride were added to 20 ml of DMF. The reaction system was then stirred at a reaction temperature kept at 100° C. for 10 hours. After the completion of the reaction, water and concentrated hydrochloric acid were added to the reaction system so that it was acidified. The resulting crystal was filtered off, and then recrystallized from isopropyl alcohol to obtain 1.5 g (7.8 mml) of 5-(4-methylthiophenyl)-tetrazole (Compound (III)) (m.p. 222° C.).

Provenance & Evidence