HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → 7,8-Dihydro-2-(phenylmethoxy)-5(6H)-quinolinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | 2-Hydroxy-7,8-dihydro-5(6H)-quinolinone | HCID 267450 | — |
| Catalyst | HCID 178418647 | HCID 178418647 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 7,8-Dihydro-2-(phenylmethoxy)-5(6H)-quinolinone | HCID 10444977 | 89% |
Reaction Steps
A suspension of 5,6,7,8-tetrahydro-5-oxo-2(1H)-quinolinone (33.0 g), silver carbonate (35.0 g), benzyl bromide (44.4 g), and toluene (400 ml) was stirred at room temperature for 72 hrs. The mixture was filtered and the filtrate was concentrated. Trituration of the residue with petroleum ether gave 45.6 g (83%) of product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05310914 |
| Source dataset | uspto-grants-1994_05 |
| ORD ID | ord-9a4cb8125e774473a9f8691548d992e6 |
| Source note | uspto-grants-1994_05 |