Water → HCID 15010194, compound

HRID 1033588Notes

Reaction equation

HRID 1033588 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[NH:12][C:11]([C:13]#[N:14])=[CH:10][C:9]=2[C:15]#[N:16])=[CH:4][CH:3]=1.[Br:17]Br.O>O1CCOCC1>[Br:17][C:10]1[C:9]([C:15]#[N:16])=[C:8]([C:5]2[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][CH:6]=2)[NH:12][C:11]=1[C:13]#[N:14]

Participants

5

Reactant 3

HCID 962WaterHCID 24408BromineHCID 15010190HCID 15010190, compound

Product 1

HCID 15010194HCID 15010194, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent2×

Procedure

A sample of 5-(p-chlorophenyl)pyrrole-2,4-dicarbonitrile (1.0 g, 0.004 mole) is dissolved in 20 mL of dioxane and-a solution of bromine (0.8 g, 0.005 mole) in dioxane (10 mL) is then added thereto. The solution is stirred several hours at room temperature and then poured into water precipitating a white solid (1.2 g, 100%). The solid has a m.p. >225° C. and a mass spectrum of a sample gives a pattern consistent with the desired structure.

Workup

  1. additionis then added
  2. customa mass spectrum of a sample gives a pattern consistent with the desired structure

Sources & evidence

ORD record
ord-81f52bd755d94cf3a580121a85a1dce1
Source dataset
uspto-grants-1994_05
Patent number
US05310938

Reaction notes

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